Recombinant Human Serum Albumin (rHSA), Yeast
Yeast-derived rHSA, supplied as an Animal-Origin-Free 20% liquid solution for cell culture, formulation and bioprocess development.
Canvax™ Yeast-Derived Recombinant Human Serum Albumin (rHSA) is a high-purity recombinant protein produced in Pichia pastoris. It provides an Animal-Origin-Free (AOF) alternative to human plasma-derived albumin for research and bioprocess development.
This ready-to-use 20% liquid solution offers ≥95% protein purity and ≥95% monomer content. Its controlled protein quality makes it suitable for cell culture, protein stabilization, and biopharmaceutical formulation development.
Recombinant human serum albumin helps stabilize proteins, minimize aggregation, and reduce non-specific surface adsorption. These properties support various biological formulations and downstream bioprocessing applications. However, users should evaluate its performance under their specific formulation conditions.
rHSA Rice-derived also available.
Looking for GMP-grade recombinant human serum albumin? Canvax also offers a separate GMP-grade rHSA option for regulated biomanufacturing projects. Contact our team to discuss availability, technical documentation, and manufacturing requirements.
Price: 1,250.00 €
Detailed information:
Advantages & Features
- Animal-Origin-Free (AOF): Recombinant human serum albumin produced in Pichia pastoris, providing an alternative to human plasma-derived albumin.
- High Purity: ≥95% protein purity for research and bioprocess development applications.
- High Monomer Content: ≥95% monomer content determined by SEC-HPLC, with controlled high- and low-molecular-mass species.
- Ready-to-Use 20% Solution: Supplied in liquid format at 190–210 mg/mL, eliminating the need for powder reconstitution.
- Formulation Support: Suitable for evaluation as a stabilizing protein component in biopharmaceutical formulations and biological processing workflows.
- Defined Quality Specifications: Batch release testing covering identity, concentration, purity, molecular size distribution and additional quality attributes.
- R&D-to-GMP Continuity: Representative R&D material for process evaluation prior to transition to the corresponding GMP-grade version.
Specifications
- Expression system: Pichia pastoris
- Animal-origin status: Animal-Origin-Free
- Molecular weight: 67 kDa
- Protein length: 585 amino acids
- Form: Liquid, 20% solution
- Protein concentration: 190–210 mg/mL
- Purity: ≥95%
- Monomer content, SEC-HPLC: ≥95%
- High-molecular-mass species: ≤5%
- Low-molecular-mass species: ≤5%
- pH: 6.7–7.3
Includes
-1 x 50 mL of yeast-derived rHSA 20% solution (10 g nominal protein content).
Download documentation
Datasheet MSDS BrochureApplications
Canvax Yeast-Derived rHSA can be evaluated for a range of research and bioprocess development applications:
- Cell Culture and Cell Processing: Protein supplement for serum-free or low-serum cell culture systems and cell handling workflows.
- Biopharmaceutical Formulation Development: Stabilizing component for research formulations involving recombinant proteins, antibodies, vaccines and viral vectors.
- Cryopreservation and Cell Washing: Protein component for the development of cell washing buffers, cryopreservation media and related formulations.
- Downstream Bioprocessing: Protective protein component for evaluation during filtration, product handling, processing and storage.
Tables & Figures
Quality Control
Each manufactured batch is released against predefined quality specifications.
Quality control testing includes:
-
- Identity
- Protein concentration
- Purity
- Monomer content
- High- and low-molecular-mass species
- Host cell proteins
- Bacterial endotoxins
- Sterility
A lot-specific Certificate of Analysis (CoA) is available upon request.
Advice
Use aseptic techniques when opening, diluting and handling the product. Evaluate the appropriate working concentration and formulation conditions according to the intended research application.
Storage & Shipping
- Storage: Store at 2–8 °C. Do not freeze.
- Shipping: Shipped with gel packs.
Citations
Safety Statements
This product is supplied exclusively for Research Use Only (RUO). It is not intended for diagnostic or therapeutic use and must not be administered directly to humans or animals. For additional safety information, please consult the Safety Data Sheet available on this website.
GMP-grade batches are available upon request for clients requiring full compliance and regulatory documentation.
Customers Review
Synonym(s)
Human serum albumin recombinant, rHSA protein, Recombinant HSA, Albumin human protein, Human albumin recombinant
Also known as:
- Spanish: Albúmina sérica humana recombinante, rHSA, Albúmina humana recombinante
- French: Albumine sérique humaine recombinante, rHSA, Albumine humaine
- German: Rekombinantes humanes Serumalbumin, rHSA, Humanalbumin
- Italian: Albumina sierica umana ricombinante, rHSA, Albumina umana
FAQs
What is yeast-derived recombinant human serum albumin?
Yeast-derived recombinant human serum albumin (rHSA) is a recombinant form of human serum albumin produced using a yeast expression system rather than extracted from human plasma. Canvax rHSA is expressed in Pichia pastoris and supplied as an Animal-Origin-Free 20% liquid solution.
What is the difference between yeast-derived rHSA and plasma-derived human serum albumin?
Yeast-derived rHSA is manufactured using a recombinant expression system, whereas plasma-derived human serum albumin is obtained from human plasma. Recombinant production provides an alternative that does not require human plasma as the protein source.
Is Canvax yeast-derived rHSA Animal-Origin-Free?
Yes. Canvax yeast-derived recombinant human serum albumin is described as Animal-Origin-Free (AOF) and is produced using a Pichia pastoris expression system.
What is the concentration of Canvax recombinant human serum albumin?
Canvax yeast-derived rHSA is supplied as a ready-to-use 20% liquid solution, with a specified protein concentration of 190–210 mg/mL. Each vial contains 50 mL, corresponding to approximately 10 g of recombinant human serum albumin.
Is Canvax recombinant human serum albumin available in GMP grade?
Yes. Canvax offers a corresponding GMP-grade version produced using the same recombinant albumin expression platform and supplied as a 20% liquid formulation. Contact Canvax for GMP-grade availability and supporting documentation.
How should yeast-derived recombinant human serum albumin be stored?
Store Canvax yeast-derived rHSA at 2–8 °C. Do not freeze. The product is shipped with gel packs.
Lukas Weber –
When selecting recombinant proteins for our formulation work, we also consider where the material is manufactured. Having a European source of yeast-derived human serum albumin is particularly valuable for our team, as we prefer working with suppliers closer to our facilities. The 20% liquid format is also convenient for preparing different working concentrations.
Mathieu Lefèvre –
We are currently evaluating recombinant albumin for a project that may eventually require GMP-grade raw materials. What caught our attention was the possibility of obtaining a GMP-grade version of the same yeast-derived protein upon request. This is an important consideration for us when selecting materials during early formulation development, as we want to anticipate future manufacturing requirements.